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Acute Inflammatory Response via Neutrophil Activation Protects Against the Development of Chronic Pain (2022)

Parisien, M., Lima, L. V., Dagostino, C., El-Hachem, N., Drury, G. L., Grant, A. V., Huising, J., Verma, V., Meloto, C. B., Silva, J. R., Dutra, G. G., Markova, T., Dang, H., Tessier, P. A., Slade, G. D., Nackley, A. G., Ghasemlou, N., Mogil, J. S., Allegri, M., … Diatchenko, L. (2022). Acute inflammatory response via neutrophil activation protects against the development of chronic pain. Science Translational Medicine, 14(644).

Quick Summary

Some acute pain transitions to chronic pain but why this occurs is not fully elucidated. This research article examined the immune system response via transcriptomic analysis in human and animal immune cell models. The authors found that inflammatory ...

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Chronic Pain